In a placebo-controlled trial of 74 patients with copperhead envenomation published in 2017,‡ CroFab® administration resulted in improved limb function vs. placebo on Day 14 post envenomation.3
Scheduled maintenance dosing after initial control lowered incidence of coagulation abnormalities due to residual venom.1
1. CroFab® [prescribing Information]. BTG International Inc; May 2017. 2. Data on file. Conshohocken, PA; BTG International Inc. 2015. 3. Gerardo CJ, Quackenbush E, Lewis B, et al. The efficacy of crotalidae polyvalent immune fab (ovine) antivenom versus placebo plus optional rescue therapy on recovery from copperhead snake envenomation: A randomized, double-blind, placebo-controlled clinical trial. Ann Emerg Med. 2017; 70(2):233-244. 4. Dart RC, Seifert SA, Boyer LV, et al. A randomized multicenter trial of crotalinae polyvalent immune Fab (ovine) antivenom for the treatment for crotaline snakebite in the United States. Arch Intern Med. 2001;161(16):2030-2036.